Physical activity and digestive system cancer risk: Still chasing the promise
A partir des données de la cohorte "Health Professionals Follow-up Study" incluant 43 479 participants masculins, cette étude prospective évalue l'association entre la pratique d'une activité physique, en fonction de sa nature et de son intensité, et le risque de cancers du système digestif (bouche, oesophage, côlon-rectum, pancréas, foie, vésicule biliaire)
The promise of health behaviors to prevent cancer was established in the landmark 1981 publication by Doll and Peto,1 who estimated that 30% of cancer deaths were attributable to lifestyle and environmental factors. Though Doll and Peto did not address physical activity or exercise, shortly thereafter, in 1984, another landmark publication by Garabrant et al2 established physical activity as a potential major factor related to colon cancer risk. In that study, the authors observed that men diagnosed with colon cancer were more likely than noncancer controls to have occupations requiring low levels of physical activity. Numerous subsequent observational studies and, more recently, randomized controlled trials have interrogated the role of physical activity and other lifestyle behaviors as risk factors related to a range of cancers.3,4