Expanding Clinical Trial Networks in Pediatric Acute Lymphoblastic Leukemia
Mené dans 15 pays sur 5 060 patients pédiatriques atteints d'une leucémie lymphoblastique aiguë, cet essai évalue l'impact d'un traitement d'intensification en fonction du risque de récidive
Treatment of pediatric acute lymphoblastic leukemia (ALL) is one of the major successes in cancer medicine. Fifty years ago, this disease was incurable. Today, a child diagnosed with ALL in high income countries in North America, Western Europe, Australia, New Zealand or Japan has a better than 90% chance of surviving 5 years, with expected cure rates above 85%. However, most children who develop ALL do not live in one of these countries, all of which have highly developed health care systems; they live in countries with fewer resources...