Why have protein biomarkers not reached the clinic?
Cet article analyse les difficultés relatives à la traduction en clinique des résultats de recherches fondamentales sur les biomarqueurs du cancer
It is disappointing that despite the substantial advances in our understanding of the molecular basis of disease, there is a paucity of approved biomarkers. Protein biomarkers in biological fluids in particular, have the potential to inform regarding risk of disease or to allow early detection for more effective treatment.
Genome Medicine , commentaire, 2010