Diffusion-Weighted Magnetic Resonance Imaging Detects Local Recurrence After Radical Prostatectomy: Preliminary Results
Menée sur 5 patients atteints d'un cancer de la prostate et ayant subi une prostatectomie radicale, cette étude montre qu'un examen réalisé à l'aide de l'imagerie par résonance magnétique pondérée en diffusion peut permettre de détecter les récidives localisées
Current conventional cross-sectional imaging techniques, such as contrast-enhanced computed tomography and magnetic resonance imaging (MRI), are largely inaccurate in detecting local recurrence after radical prostatectomy. We report on five patients with biochemical recurrence after radical retropubic prostatectomy and pelvic lymph node dissection for whom local recurrence could only be detected with diffusion-weighted (DW) MRI. Prior to DW-MRI, all patients had negative digital rectal examinations, negative or equivocal conventional cross-sectional imaging, and negative bone scans. All suspicious lesions on DW-MRI imaging were histologically proved to be local recurrences of prostate cancer after either transrectal ultrasound–guided or transurethral biopsy. These results should encourage other centres to test our findings.
European urology , résumé, 2010