Health-Related Quality of Life by Race, Ethnicity, and Country of Origin among Cancer Survivors
Menée aux Etats-Unis à partir de données portant sur 5 366 patients ayant survécu à un cancer (âge moyen : 59,8 ans), cette étude analyse leur qualité de vie en fonction de leur origine ethnique et de leur pays d'origine
Background: Typical cancer research studies of health-related quality of life (HRQOL) in the United States do not include country of origin when examining race and ethnic group differences. This population-based, cross-sectional study used an innovative methodology to examine how self-reported racial and ethnic groups, by country of origin, report differential HRQOL experiences after adjusting for clinical and demographic characteristics including socio-economic status. Methods: Recruited from four cancer registries in California, Louisiana, and New Jersey, cancer survivors completed Patient-Reported Outcomes Measurement Information System® (PROMIS®) measures of fatigue, pain interference, anxiety, depression, sleep disturbance, physical function, ability to participate in social roles, and cognitive function. Latent profile analysis clustered survivors in HRQOL clusters based on including all the PROMIS domains. Results : The 5366 participants (60% female; 40% male; average age of 59.8 years) included 17% Asian, 18% Black, 21% Hispanic, and 41% White survivors. Survivors were grouped into four clusters: High HRQOL (26%); Average HRQOL (34%); Low HRQOL (29%); and Very Low HRQOL (11%). Among many differences by race, ethnicity, and country of origin, Caribbean cancer survivors were more likely to be in the Very Low HRQOL cluster (OR, 2.67; 95% CI, 1.31-5.43) compared to non-Hispanic White survivors. Similarly, American Indian and Alaska Native, Cuban, Dominican, and Puerto Rican cancer survivors had relatively high percentages in the Very Low HRQOL cluster. Conclusions: This study found significant differences in HRQOL experience by race, ethnicity, and country of origin, even after adjusting for social determinants of health. These findings inform future HRQOL research to include these self-reported factors.