Gastric cancer incidence among Hispanics in California: patterns by time, nativity, and neighborhood characteristics
A partir des données du registre californien des cancers entre 1998 et 2002, cette étude analyse les caractéristiques de l'incidence du cancer de l'estomac dans la population hispanique
Background: Better understanding about gastric cancer incidence patterns among Hispanics by birthplace, socioeconomic status (SES) and acculturation can improve preventive strategies and disease models. Methods: Incidence rates, rate ratios, and estimated annual percent change (EAPC) in rates of anatomic and histologic subtype-specific gastric cancer were calculated by age, sex, and nativity among Hispanics using California Cancer Registry data from 1988 through 2004. Incidence rates in 1998-2002 were compared by neighborhood SES and Hispanic enclave status according to 2000 US Census data. Results: Incidence rates of diffuse gastric cancer increased from 1988 through 2004 among foreign-born Hispanic men (EAPC: 3.5%, 95% CI: 1.5%-5.5%) and US-born Hispanic women (EAPC: 3.0%, 95% CI: 0.7%-5.3%). During the same time period, incidence rates of intestinal gastric cancer declined significantly and both cardia and non-cardia gastric cancer were steady or declined among foreign-born and US-born Hispanic men and women. Non-cardia and both intestinal and diffuse gastric cancer were more common in foreign-born than US-born Hispanic men and women, and in those from lower-SES, higher-enclave neighborhoods. By contrast, among younger and middle-aged Hispanic men, cardia tumors were more common in the US-born than the foreign-born, and in higher-SES, lower-enclave neighborhoods. Conclusions: Varying gastric cancer risk factors among Hispanic subgroups and increasing rates of diffuse gastric cancer in foreign-born Hispanic men and US-born Hispanic women merit further investigation to identify separate disease etiologies. Impact: Age, sex, birthplace, SES, and acculturation modify gastric cancer incidence in Hispanics and should be considered when examining disease risk and prevention.