The immune contexture in human tumours: impact on clinical outcome
Cet article passe en revue les travaux récents sur les différents rôles attribués aux cellules immunitaires infiltrantes dans la progression tumorale
Tumours grow within an intricate network of epithelial cells, vascular and lymphatic vessels, cytokines and chemokines, and infiltrating immune cells. Different types of infiltrating immune cells have different effects on tumour progression, which can vary according to cancer type. In this Opinion article we discuss how the context-specific nature of infiltrating immune cells can affect the prognosis of patients.