Diabetes and Cancer: Unravelling the Complexity
Menée aux Etats-Unis à partir de données portant sur une cohorte de 113 429 femmes et une cohorte de 45 604 hommes, cette étude évalue l'association entre la durée d'un diabète de type 2 et le risque de cancer
In the face of an ongoing epidemic of both obesity and diabetes1there is great interest in understanding, and ameliorating, the impact of these conditions on a broad range of cancers.In arecentreview,2type 2 diabetes mellitus (T2DM) was associated with increased risk of breast, colorectal, endometrial, pancreatic, hepatic and bladder cancerbut not prostate cancer.In relation to obesity, IARC3foundthere was sufficient evidence to link absence of excess body-fatness to prevention of the following cancers: esophageal (adenocarcinoma), gastric cardia, colon and rectum, liver, gallbladder, pancreas, postmenopausalbreast, corpus uteri, ovary, renal cell, meningioma, thyroid and multiple myeloma (and limited or inadequate evidence for other cancers).