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Monoclonal Antibody-Based Therapies: A New Dawn in the Treatment of Acute Lymphoblastic Leukemia

Cet article passe en revue les travaux récents sur le développement de traitements à base d'anticorps monoclonaux dans la leucémie lymphoblastique aiguë

Modern multiagent chemotherapy regimens have increased the cure rate in acute lymphoblastic leukemia (ALL). In pediatric ALL, refinements of doses and schedules of chemotherapy combinations have increased the cure rate from less than 40% in the 1960s to 80% in 2000 without the addition of any novel chemotherapy drugs or targeted therapies...

Journal of Clinical Oncology 2012

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