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Cancer therapy: Tumours switch to resist

Menée à l'aide d'un modèle murin de mélanome, cette étude met en évidence un mécanisme de résistance à un traitement par transfert adoptif de cellules T

Tumour cells can respond to targeted immune-cell therapies by losing proteins that mark them as being cancerous. Subverting this resistance mechanism may lead to more durable cancer-treatment strategies.Tumour cells can respond to targeted immune-cell therapies by losing proteins that mark them as being cancerous. Subverting this resistance mechanism may lead to more durable cancer-treatment strategies.

Nature , commentaire, 2011

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