MSCs, Macrophages, and Cancer: A Dangerous Ménage-à-Trois
Ces deux études mettent en évidence des mécanismes impliquant les cellules stromales mésenchymateuses dans la croissance tumorale
Two studies in this issue of Cell Stem Cell highlight context-dependent roles for MSCs in controlling tumor growth. Lee et al. (2012) show that preactivated MSCs have antitumor effects upon adoptive transfer in vivo, and Ren et al. (2012) show that tumor-resident MSCs can promote tumor growth by influencing macrophages.
Cell stem cell , commentaire, 2011