JAKs and STATs in Immunity, Immunodeficiency, and Cancer
Cet article passe en revue le rôle des voies de signalisation JAK et STAT dans l’immunité, l’immunodéficience et les cancers
A large number of cytokines signal through the JAK–STAT pathway. Abnormal function of this pathway may lead to a variety of diseases. Targeting the defects in this signaling pathway has already led to treatment advances, and further advances are likely.