Recurrent Hepatocellular Carcinoma: It’s the Virus!
Mené sur 780 patients atteints d'un carcinome hépatocellulaire associé au virus de l'hépatite B, cet essai évalue l'intérêt d'un traitement à base d'analogues nucléosidiques/nucléotidiques pour améliorer la survie des patients après une hépatectomie radicale
Hepatocellular carcinoma (HCC) remains a dreaded complication of chronic hepatitis B virus (HBV) infection. Surgical resection is the treatment of choice for patients with early-stage disease and preserved liver function. However, even successful surgical resection is fraught with high rates of disease recurrence limiting overall survival. In those patients with curative surgical potential, optimizing medical care should be an essential component of a therapeutic strategy to maximize outcome. In this regard, antiviral therapy forHBVmay play an important role...
Journal of Clinical Oncology , éditorial en libre accès, 2013