Colorectal-Cancer Screening — Coming of Age
Mené dans l'Etat du Minnesota auprès de 46 551 participants (âge : 50 à 80 ans ; durée de suivi : 30 ans), cet essai randomisé évalue l'effet à long terme, sur la mortalité spécifique et la mortalité toutes causes confondues, d'un dépistage annuel ou biennal du cancer colorectal par un test de recherche de sang occulte dans les selles
The Minnesota Colorectal Cancer Control Study showed 20 years ago that the annual use of the guaiac fecal occult-blood test decreased mortality from colorectal cancer by 33%. A few years later, colorectal-cancer screening was endorsed by multidisciplinary guidelines and was covered by insurance, leading to an increase in the performance of colorectal-cancer screening tests. Two articles in this issue of the Journal provide evidence of what colorectal-cancer screening can accomplish over the long term.
Nishihara and colleagues found decreased risks of colorectal cancer and death from colorectal cancer associated with screening colonoscopy and sigmoidoscopy, following two well-described prospective cohorts...
New England Journal of Medicine , éditorial, 2012