The roles of TGF
Cet article passe en revue les travaux récents sur les mécanismes par lesquels, via la régulation des composants du micro-environnement, la signalisation du facteur TGF
The influence of the microenvironment on tumour progression is becoming clearer. In this Review we address the role of an essential signalling pathway, that of transforming growth factor-
β
, in the regulation of components of the tumour microenvironment and how this contributes to tumour progression.