Relationship between vegetable and carotene intake and risk of prostate cancer: the JACC study
Menée à partir d'une enquête auprès d'une cohorte de 15 471 participants, cette étude japonaise évalue l'association entre la consommation de légumes ou de carotène et le risque de cancer de la prostate (143 cas)
Background : We examined the associations of intakes of vegetables and carotenes with risk of prostate cancer in Japanese. Methods : A total of 15 471 Japanese men participating in the Japan Collaborative Cohort study completed a questionnaire including food intake. Of them, 143 incident prostate cancers were documented. We examined the associations stated above by using Cox proportional hazard model. Results : Vegetable intake was not associated with the risk of prostate cancer, but so was dietary alpha-carotene intake. The multivariable hazard ratio (95%CI) in the secondary highest and highest quintiles of alpha-carotene intake was 0.50 (0.26–0.98) (P=0.043) and 0.46 (0.22–0.97) (P=0.041) (P for trend=0.224), respectively. Beta-carotene intake was not associated with the risk of prostate cancer. Conclusion : Alpha-carotene intake was associated with lower risk of prostate cancer among Japanese.