Autophagy-Mediated Tumor Promotion
Cet article passe en revue les travaux récents sur le rôle de l'autophagie dans la croissance tumorale
Mouse models for cancer are revealing novel cancer-promoting roles for autophagy. Autophagy promotes tumor growth by suppressing the p53 response, maintaining mitochondrial function, sustaining metabolic homeostasis and survival in stress, and preventing diversion of tumor progression to benign oncocytomas.