Statin use is not associated with reduced risk of skin cancer: a meta-analysis
A partir d'une revue de la littérature publiée jusqu'en juin 2013 (29 études), cette méta-analyse montre que l'utilisation de statines n'est pas associée à une réduction du risque de cancer de la peau
Background : There is contradictory evidence about the association between statin and skin cancer. Methods : Literature search in PubMed and Web of Science was undertaken up to June 2013. Pooled relative risk (RR) estimates and 95% confidence intervals (CIs) were calculated. Result : A total of 21 articles with 29 studies were identified. No association was found between statin and skin cancer among neither melanoma (RR, 0.94; 95% CI, 0.85–1.04) nor non-melanoma skin cancer (RR, 1.03; 95% CI, 0.90–1.19). Conclusion : Our meta-analysis does not support a potential role of statin use in the prevention of skin cancer.