Stereotactic body radiotherapy: A critical review for non–radiation oncologists
Cet article présente la procédure et la technologie permettant de délivrer de manière efficace et sécurisée une radiothérapie stéréotaxique corporelle, puis fait le point sur les indications, les résultats et les limites associés à ce type de traitement dans le cadre d'un cancer métastatique, d'un cancer du poumon ou du foie
Stereotactic body radiotherapy (SBRT) involves the treatment of extracranial primary tumors or metastases with a few, high doses of ionizing radiation. In SBRT, tumor kill is maximized and dose to surrounding tissue is minimized, by precise and accurate delivery of multiple radiation beams to the target. This is particularly challenging, because extracranial lesions often move with respiration and are irregular in shape, requiring careful treatment planning and continual management of this motion and patient position during irradiation. This review presents the rationale, process workflow, and technology for the safe and effective administration of SBRT, as well as the indications, outcome, and limitations for this technique in the treatment of lung cancer, liver cancer, and metastatic disease.