Broader Implications of a Stage-Guided Stratified Therapeutic Approach for AIDS-Related Kaposi’s Sarcoma
Mené sur 469 patients atteints d'un sarcome de Kaposi associé à un sida, cet essai évalue l'intérêt d'une stratification par stade pour réduire l'exposition à une chimiothérapie (durée médiane de suivi : 4,6 ans)
Kaposi sarcoma (KS) remains the most common illness in people living with HIV (PLWH), although its incidence has declined dramatically since the introduction of combination antiretroviral therapy (cART). Unlike most malignancies that are staged using the TNM system, which takes into account tumor size and extent of spread, staging for AIDS-related KS must account for the presence of other AIDS-related effects, such as the severity of immunosuppression and presence of opportunistic infections...
Journal of Clinical Oncology , éditorial en libre accès, 2013