Adjuvant chemotherapy for local relapse breast cancer
Mené sur 162 patientes présentant une récidive locorégionale isolée d'un cancer du sein, cet essai randomisé international évalue l'efficacité, du point de vue de la survie sans maladie, et la toxicité d'une chimiothérapie adjuvante, notamment en fonction du statut des récepteurs aux œstrogènes
Patients with isolated locoregional recurrences of breast cancer have a high risk of distant metastasis and death from cancer. The main objective in this clinical setting is curative treatment, which consists of radical surgery with or without complementary radiotherapy. The targeted localisations include soft tissue of the ipsilateral conserved breast or of the chest wall, mastectomy scar or skin, and lesions in the ipsilateral axillary lymph nodes, extranodal soft tissue of the ipsilateral axi ...
The Lancet Oncology , commentaire, 2013