HPV Vaccination is Associated with Reduced Risk of Cervical Lesions in Denmark
Menée sur une cohorte de 399 244 jeunes femmes nées entre 1989 et 1999 et à partir des données 2006-2012 des registres danois, cette étude évalue, 6 ans après son homologation et son implémentation dans un programme de vaccination, l'effet du vaccin quadrivalent ciblant le papillomavirus humain de type 6, 11, 16 ou 18 sur le risque de lésions cervicales pré-cancéreuses
Two HPV vaccines are currently available and have proven to be highly effective against HPV16/18-associated cervical cancer. One of these vaccines, a quadrivalent vaccine, was licensed in Denmark in 2006, and it was subsequently incorporated into general childhood vaccination programs for girls free of charge and was made available to girls and women and to boys and men not covered by the program for a fee. To date, a nationwide population-based study of HPV-related cervical abnormalities in vaccinated vs unvaccinated women based on information on vaccination status at the individual level has not been reported...
Journal of the National Cancer Institute , commentaire en libre accès, 2014