Gastric Cancer: Descriptive Epidemiology, Risk Factors, Screening, and Prevention
Cette étude passe en revue l'évolution de l'incidence, de la survie et de la mortalité associées au cancer de l'estomac, ainsi que les facteurs de risque environnementaux ou génétiques, et les statégies de détection précoce et de prévention
Less than a century ago, gastric cancer (GC) was the most common cancer in the United States and perhaps throughout the world. Despite its worldwide decline in incidence over the past century, GC remains a major killer across the globe. This article reviews the epidemiology, screening, and prevention of gastric cancer. We first discuss the descriptive epidemiology of GC, including its incidence, survival, and mortality, including trends over time. Next, we characterize the risk factors for gastric cancer, both environmental and genetic. Serological markers and histological precursor lesions of GC and early detection of GC of using these markers is reviewed. Finally, we discuss prevention strategies and provide suggestions for further research.