Stem cell-based therapies for cancer treatment: separating hope from hype
Cet article passe en revue les perspectives offertes par le développement de traitements à base de cellules souches pour les patients atteints de cancer
Stem cell-based therapies are emerging as a promising strategy to tackle cancer. Multiple stem cell types have been shown to exhibit inherent tropism towards tumours. Moreover, when engineered to express therapeutic agents, these pathotropic delivery vehicles can effectively target sites of malignancy. This perspective considers the current status of stem cell-based treatments for cancer and provides a rationale for translating the most promising preclinical studies into the clinic.