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What proportion of cancer deaths in the contemporary United States is attributable to cigarette smoking ?

Menée aux Etats-Unis à partir des données 2010 d'une enquête nationale portant sur plus de 18 000 participants et des données de 5 études incluant au total 421 378 hommes et 532 651 femmes, cette étude estime la fraction attribuable au tabagisme pour les décès par cancer chez les adultes âgés de 35 ans ou plus

Purpose : The proportion of cancer deaths in the contemporary U.S. caused by cigarette smoking (the population attributable fraction (PAF)) is not well-documented.

Methods : The PAF of all cancer deaths due to active cigarette smoking among adults 35 and older in the U.S. in 2010 was calculated using age and sex-specific smoking prevalence from the National Health Interview Survey (NHIS) and age and sex-specific relative risks from the Cancer Prevention Study-II (for ages 35-54) and from the Pooled Contemporary Cohort data set (for ages 55 and older).

Results : The PAF for active cigarette smoking was 28.7% when estimated conservatively, including only deaths from the 12 cancers currently formally established as caused by smoking by the U.S. Surgeon General. The PAF was 31.7% when estimated more comprehensively, including excess deaths from all cancers. These estimates do not include additional potential cancer deaths from environmental tobacco smoke or other type of tobacco use such as cigars, pipes or smokeless tobacco.

Conclusions : Cigarette smoking causes a large proportion of cancer deaths in the contemporary U.S. Reducing smoking prevalence as rapidly as possible should be a top priority for U.S. public health efforts to prevent cancer deaths.

Annals of Epidemiology , résumé, 2013

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