Detection of DCIS and reduced invasive interval cancers
Menée au Royaume-Uni à partir de données portant sur 5 243 658 femmes ayant participé entre 2003 et 2007 au dépistage organisé du cancer du sein (âge : 50 à 64 ans), cette étude évalue l'association entre la proportion de carcinomes canalaires in situ détectés et le taux de cancer invasif diagnostiqué entre deux examens de dépistage
When breast screening began in the UK, such was the uncertainty concerning the benefits and harms of detecting ductal carcinoma in situ (DCIS) that national guidelines specified an upper limit as well as a lower limit for detection by individual screening centres. This was only changed when an association was shown between DCIS detection and small invasive cancer detection in the National Health Service Breast Screening Programme. Nonetheless, controversy regarding the pros and cons of DCIS detection at screening has continued to this day.
The Lancet Oncology , commentaire, 2014