Treatment of regional lymph nodes in breast cancer—not recommended for all patients with 1 to 3 positive auxiliary nodes
Ces deux articles présentent des opinions opposées quant à la pertinence d'une radiothérapie des ganglions régionaux chez les patientes atteintes d'un cancer du sein
Should all women with positive nodes in breast cancer receive comprehensive nodal irradiation?—No.
I would say that some node-positive patients should get comprehensive nodal irradiation (RT), but I don’t believe the current data supports its use in all node-positive patients, particularly in patients with 1 to 3 positive nodes. Advocates for routine use of comprehensive nodal RT in node-positive patients point to 2 main sources: the Early Breast Cancer Trialists’ Collaborative Group (EBCTCG) meta-analysis of post-mastectomy RT (PMRT),1 and the MA.20 clinical trial...
JAMA Oncology , article en libre accès, 2015