The global challenge of colorectal cancer
Menée dans 195 pays, cette étude analyse, sur la période 1990-2017, les disparités géographiques dans l'évolution de l'incidence du cancer colorectal, des années de vies perdues ajustées sur l'incapacité et de la mortalité en fonction des différents facteurs de risque
Colorectal cancer is the third most commonly diagnosed cancer in men and the second most common cancer in women, and is also the second leading cause of cancer death worldwide. The incidence of colorectal cancer varies greatly across countries and by world regions, and is associated with level of socioeconomic development. Incidence is higher in regions higher on the Human Development Index (HDI), and lower in regions that are lower on the HDI. In The Lancet Gastroenterology & Hepatology, the GBD 2017 Colorectal Cancer Collaborators report on the incidence, mortality, and disability-adjusted life-years (DALYs) of colorectal cancer in 195 countries and territories from 1990 to 2017. Incidence, mortality, and DALYs were estimated using sample vital registration, verbal autopsy, and cancer registry data, along with Socio-demographic Index and Healthcare Access and Quality Index data. The incidence of colorectal cancer was estimated to be 1·8 million (95% uncertainty interval 1·8–1·9) in 2017, an increase of 9·5% (4·5–13·5) since 1990, with an estimated 896 000 (876 300–915 700) deaths from colorectal cancer, which had decreased since 1990 (−13·5% [–18·4 to −10·0]). The authors show that there are substantial regional differences in incidence and mortality globally, and also in the percentage change in age-standardised incidence rates. An estimated 19·0 million (18·5–19·5) DALYs were reported in 2017, demonstrating the high burden of colorectal cancer on individuals and society.(..)