SIgmoidoscopy screening for colorectal cancer
Mené en Norvège auprès de 98 678 personnes âgées de 50 à 64 ans (durée médiane de suivi : 14,8 ans), cet essai évalue, en fonction du sexe et du point de vue de la réduction de l'indicence du cancer colorectal et de la mortalité spécifique, l'intérêt d'un dépistage du cancer colorectal par sigmoïdoscopie flexible en combinaison ou non avec un test de recherche de sang occulte dans les selles
What is the problem and what is known about it so far?
Two of the most popular procedures to screen for cancer of the colon and rectum are colonoscopy and sigmoidoscopy. Colonoscopy uses a 4-foot-long, flexible tube about the thickness of a finger that is inserted into the person's anus and then advanced. The doctor looks through the other end, takes pictures, and sometimes takes small samples of tissue. This procedure can examine all of the places where colorectal cancer occurs, but it often requires sedation, which means that the person needs help getting home afterward. Sigmoidoscopy is similar except that the scope is advanced a shorter distance into the bowel; it also examines only some of the places where colorectal cancer occurs, and sedation usually is not necessary. Both procedures have been used for years, but we still need more information about who should be screened and how.
Annals of Internal Medicine , article en libre accès, 2017