• Dépistage, diagnostic, pronostic

  • Évaluation des technologies et des biomarqueurs

  • Prostate

What should doctors say to men asking for a PSA test?

A partir d'une revue systématique de la littérature publiée jusqu'en avril 2018 (5 essais incluant au total 721 718 hommes), cette méta-analyse évalue l'effet d'un dépistage du cancer de la prostate par dosage sérique de l'antigène prostatique spécifique sur la mortalité spécifique et la mortalité globale

Patients need individual discussions about the benefits and harms of testingA BMJ Rapid Recommendation in this issue1 reviews the evidence2 behind prostate cancer screening, including the latest large trial of prostate cancer screening with the prostate-specific antigen (PSA) test which showed no difference in prostate cancer mortality after 10 years.3 Neither the US Preventive Services Task Force4 nor Public Health England5 recommend population screening as there is little evidence that screening would reduce deaths from prostate cancer. However, both countries suggest that decisions about prostate cancer testing should involve discussion with individual patients of the potential benefits and harms of testing.Prostate cancer deaths are common and now exceed breast cancer deaths in the UK, in part because the ageing population makes prostate cancer more common and in part because of advances in the treatment of breast cancer. Men will therefore continue to come to their general practitioners asking for a test, and their experiences vary greatly from …

BMJ , éditorial en libre accès, 2017

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