Intelligent use of the fecal immunochemical test in population-based screening
Menée à partir de données portant sur 640 859 personnes ayant subi un test immunochimique de recherche de sang dans les selles (âge : 50 à 75 ans ; durée de suivi : 2 ans), cette étude analyse, en fonction de l'âge et du sexe des participants, l'influence des seuils de positivité sur la détection des cancers colorectaux
Population screening for colorectal cancer (CRC) is an exercise in risk assessment that balances benefits and harms within available endoscopy resources. Although missed disease in a patient with symptoms might be labeled an “error,” missed pathology in population-based screening is inevitable and varies with the performance characteristics of the screening intervention. Nationwide population-based CRC screening programs are fast becoming the norm, with the quantitative fecal immunochemical test (FIT) replacing the guaiac fecal occult blood test as the method of choice. In their Annals report, Selby and colleagues (1) describe a large community-based initiative that uses FIT.
Annals of Internal Medicine , éditorial, 2017