Impact of healthy lifestyles on cancer risk in the Chinese population
Menée en Chine à partir des données de 3 cohortes incluant au total 101 208 adultes, cette étude analyse l'association entre 6 facteurs liés à un mode de vie sain (absence de tabagisme, faible consommation d'alcool, grande consommation de fruits et légumes, ...) et le risque de cancer en fonction du sexe
Background: Although cancer has become one of the leading health burdens, to the authors’ knowledge, evidence regarding its relationship with a healthy lifestyle in the Chinese population remains limited. Methods: The authors evaluated the association between clustering of healthy lifestyle factors and cancer risk using 3 prospective cohort studies with 101,208 Chinese adults from the general population. Hazard ratios (HRs) and corresponding 95% confidential intervals (95% CIs) related to healthy lifestyle factors were calculated using Cox proportional hazard models, and population-attributable risk percentages were estimated further. Results: The results demonstrated that each additional healthy lifestyle factor was associated with a 6% (range, 3%-9%) lower risk of overall cancer. Compared with having none to 3 healthy lifestyle factors, HRs related to adherence to all 6 healthy lifestyle factors were 0.78 (95% CI, 0.60-1.02) and 0.82 (95% CI, 0.67-1.00), respectively, for men and women. It was estimated that approximately 18.4% and 2.3%, respectively, of overall cancer cases for men and women were attributable to nonadherence to all 6 healthy lifestyle factors. Conclusions: The results of the current study indicate that adherence to clustering of healthy lifestyle factors was associated with a reduced risk of cancer incidence among Chinese adults. Greater efforts urgently are needed to promote the adoption of multiple healthy lifestyle behaviors to reduce the increasing burden of cancer.