Global consequences of malignant CNS tumours: a call to action
Menée notamment à partir de données des registres des cancers, cette étude estime, en fonction de différentes échelles géographiques (régionale, nationale, mondiale), l'évolution de l'incidence des tumeurs du système nerveux central, de l'espérance de vie en bonne santé et de la mortalité sur la période 1990-2016
Tumours of the CNS are among the most feared cancers because they affect the very organ that defines personality and assures physical and cognitive independence. CNS tumours can cause severe disability, including seizures, poor memory or speech problems, and physical dysfunction. These effects can make caring for someone diagnosed with a CNS tumour challenging and often necessitate full-time assistance once the disease has progressed into its later stages. CNS tumours can affect the brain or spinal cord and occasionally can disseminate within the CSF. They might occur in individuals at any age and from any background. No environmental exposure, other than previous ionising radiation, or behavioural or lifestyle choices are known to increase the risk of developing these tumours. Atopic conditions might protect against the development of a malignant brain tumour, but the biological basis for this association in unknown
The Lancet Neurology , commentaire en libre accès, 2018