Obesity and the Importance of Cardiovascular Disease Surveillance After Colorectal Cancer
Menée à partir des données des registres américains des cancers et de la base Medicare portant sur 2 839 patients atteints d'un cancer colorectal de stade I à III diagnostiqué entre 2006 et 2011 (âge moyen : 61,9 ans), cette étude de cohorte rétrospective analyse l'association entre la composition corporelle (masse musculaire et graisseuse...) et le risque d'événements cardiovasculaires indésirables
Many colorectal cancer survivors in the United States face substantial cardiovascular disease comorbidity. Data from the Surveillance, Epidemiology, and End Results (SEER)-Medicare population indicate that more than half of those with primary stage I to III colorectal cancer after age 65 years in the United States will also be diagnosed with cardiovascular disease in the decade after cancer diagnosis.1 Increased cardiovascular disease risk in colorectal cancer survivors relative to the general population is likely attributable to multiple shared risk factors, many of which are precursors or consequences of obesity. The potential for cardiac toxic effects from cancer treatment is also a concern.
JAMA Oncology , commentaire, 2018