Screening for Pancreatic Cancer—Is There Hope?
Ce dossier présente les recommandations de l'"US Preventive Services Task Force" en matière de dépistage des cancers du pancréas
Pancreatic cancer can be a devastating disease. Fewer than 9% of patients with ductal adenocarcinoma of the pancreas are living 5 years after diagnosis. It is estimated that in 2019, about 57 000 people will be diagnosed with pancreatic cancer in the United States and that it may soon overtake colon cancer to become the second-most common cause of cancer-related death. Based on recent progress in the treatment of colon cancer, the best hope for reducing the cancer-specific mortality of pancreatic cancer may be early diagnosis and treatment.The US Preventive Services Task Force has issued a recommendation statement against screening for pancreatic cancer in asymptomatic adults (grade D recommendation), supported by a systematic review and evidence report. The recommendation statement acknowledges that screening carries risk and that there is currently no evidence that screening for pancreatic cancer is effective in reducing mortality. There are effective screening programs for other common cancers, including breast, colon and cervix. So why are screening and early diagnosis and treatment of pancreatic cancer so difficult?
JAMA Internal Medicine , éditorial, 2018