Solid organ transplantations in childhood cancer survivors: an unrealised research potential
Menée aux Etats-Unis à partir de données portant sur 13 318 patients ayant survécu au moins 5 ans à un cancer pédiatrique diagnostiqué avant l'âge de 21 ans entre 1970 et 1986, cette étude de cohorte rétrospective analyse le recours à une greffe d'organe solide après les traitements anticancéreux et la survie à 5 ans associée
Do anti-cancer and immunosuppressive agents cause cancer in man? What is the effect of these agents on existing cancers? These key fundamental questions were raised in 1972 by Penn and Starzl in their article entitled ‘The effect of immunosuppression on cancer’. Resulting speculations, which are highly relevant for the topic of solid organ transplantation in childhood cancer survivors, are considered by Andrew C Dietz and colleagues in The Lancet Oncology.
The Lancet Oncology , commentaire, 2018