Deep anaesthesia and poor outcomes: the jury is still out
Mené dans 7 pays sur 6 644 patients âgés de plus de 60 ans et atteints de pathologies diverses (dont le cancer) devant être traitées par chirurgie, cet essai randomisé évalue l'effet, sur la mortalité toutes causes confondues à 10 ans et sur la survenue d'effets indésirables (accidents cardiovasculaires, douleurs persistantes, récidive du cancer, etc.), de la profondeur de l'anesthésie générale (indice bispectral 35 ou 50)
The ideal anaesthetic depth is where the risk of operative recall or awareness is as low as possible, regardless of what is happening surgically, and where blood pressure and heart rate are kept optimal for the individual patient. Emergence from an appropriate level of anaesthesia should be prompt and uncomplicated, and without side-effects. To date, the norm has been for deeper anaesthesia, facilitated by modern short-acting drugs.
The Lancet , commentaire, 2018