Associations between self-reported physical activity, quality of life and emotional well-being in men with prostate cancer on active surveillance
Menée au Canada à partir de données portant sur 630 patients atteints d'un cancer de la prostate, cette étude rétrospective analyse l'association entre une activité physique auto-déclarée, le bien-être psychique et la qualité de vie pendant la période de surveillance active
Objective : The relationship between physical activity (PA) and quality of life (QOL) relative to active treatment for prostate cancer (PCa) has been well-studied; however, little is known about this relationship during active surveillance (AS). Moreover, whether PA is associated with better emotional well-being (EWB) in men with low-risk PCa requires further investigation. Accordingly, we examined the association between self-reported PA and the average change in QOL and EWB over time during AS. Methods : A total of 630 men on AS were included in this retrospective, longitudinal study from AS initiation until AS discontinuation. Generalized estimated equations were used to determine the association between self-reported PA (independent variable), QOL and EWB (dependent variables) over time, adjusting for participants' age. Results : QOL was higher over time in active ((95%CI) = 1.14 (0.11, 2.16), p=0.029) and highly active participants ((95%CI) =1.62 (0.58, 2.67), p=0.002) compared to their inactive counterparts. Highly active participants had 55% greater odds of experiencing high EWB relative to inactive participants (OR (95%CI) =1.55 (1.11, 2.16), p= 0.010). In men with low EWB at baseline (median = 3 months after diagnosis), the highest levels of PA (> 1000 metabolic equivalent-minutes per week) were associated with higher EWB over time (OR (95%CI) = 2.17 (1.06, 4.46), p= 0.034). Conclusion : These data further support the importance of PA as a supportive care strategy for men on AS. Our findings suggest that engaging in higher volumes of PA post-diagnosis may be beneficial particularly for men exhibiting low emotional well-being early on during AS. This article is protected by copyright. All rights reserved.
Psycho-Oncology 2020