Five-Year Follow-up of a Randomized Clinical Trial Testing Mailed Nicotine Patches to Promote Tobacco Cessation
Menée au Canada auprès de 518 personnes ayant accepté d'être recontactées, cette étude analyse le taux de sevrage tabagique 5 ans après l'envoi par courrier de cinq semaines de traitement de substitution par patchs nicotiniques
Our previous randomized clinical trial demonstrated that smokers receiving nicotine patches by mail (5 weeks of nicotine patches) were more likely to report 30-day point prevalence abstinence at 6 months compared with smokers not mailed nicotine patches. The current project extends this research by recontacting participants after 5 years. Briefly, attempts were made to recontact participants from the original randomized clinical trial (924 to be recontacted; 75 did not consent to recontact). Those contacted and providing verbal informed consent to participate in the follow-up completed a telephone interview asking about current smoking and, for those not currently smoking, length of time since tobacco cessation (ie, 30 days, 6 months, or since the last interview). Attempts were made to relocate those lost to contact. Participants reported as deceased were recorded. The primary outcome was 30-day point prevalence smoking abstinence at 5 years, and the secondary outcome was prolonged 6-month abstinence at 5 years. Analyses were conducted using SPSS version 26 (IBM) and used logistic regressions with a 2-tail test, with a P value less than .05 indicating significance. The project was approved by the Centre for Addiction and Mental Health standing institutional review board.
JAMA Internal Medicine , résumé, 2019