• Dépistage, diagnostic, pronostic

  • Découverte de technologies et de biomarqueurs

  • Mélanome

A deep learning system for differential diagnosis of skin diseases

Menée à partir de données cliniques portant sur 16 114 patients et à l'aide de clichés dermatologiques, cette étude évalue la performance, par rapport à différents professionnels de santé (dermatologues, médecins généralistes et infirmières), d'un algorithme d'apprentissage automatique pour diagnostiquer différentes pathologies cutanées dont le mélanome

Skin conditions affect 1.9 billion people. Because of a shortage of dermatologists, most cases are seen instead by general practitioners with lower diagnostic accuracy. We present a deep learning system (DLS) to provide a differential diagnosis of skin conditions using 16,114 de-identified cases (photographs and clinical data) from a teledermatology practice serving 17 sites. The DLS distinguishes between 26 common skin conditions, representing 80% of cases seen in primary care, while also providing a secondary prediction covering 419 skin conditions. On 963 validation cases, where a rotating panel of three board-certified dermatologists defined the reference standard, the DLS was non-inferior to six other dermatologists and superior to six primary care physicians (PCPs) and six nurse practitioners (NPs) (top-1 accuracy: 0.66 DLS, 0.63 dermatologists, 0.44 PCPs and 0.40 NPs). These results highlight the potential of the DLS to assist general practitioners in diagnosing skin conditions.

Nature Medicine , résumé, 2020

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