International travel to obtain medical treatment for primary retinoblastoma: a global cohort study
Menée à partir de données de 153 pays portant sur 4 351 patients atteints d'un rétinoblastome, cette étude de cohorte internationale analyse les facteurs associés à leurs déplacements au-delà des frontières de leur pays pour accéder aux traitements et soins anticancéreux
Early diagnosis and treatment of retinoblastoma (Rb), the most common intraocular malignancy, can save both the child’s life and vision. However, access to services and hence chances for survival and preserving the eye and its vision vary widely across the globe. Some families have to, or make a choice to, leave their home country to seek planned medical treatment abroad. We aimed to investigate how frequently this cross border travel occurs and the factors associated with it. A total of 278 Rb centers in 153 countries were recruited to participate in a global cross-sectional analysis of newly diagnosed Rb patients in 2017. Number and proportions of children who travelled from their home country for treatment were analysed by country, continent, socio-economic stratum, and clinical and demographic features. The cohort included 4,351 new patients of whom 223 (5.1%, 95% CI 4.5-5.8) were taken across country borders for planned medical treatment. Independently significant predictors of travelling across borders included: being from a country with a smaller population, being from a country classified as low socioeconomic status, having bilateral Rb, and having intra-ocular disease without extra-ocular spread. The factors that determine international travel for retinoblastoma treatment are complex and deserve further investigation. We may need to rethink the way services are delivered in the light of the threat of severe curtailment of international travel from pandemics like COVID-19.