Colorectal Cancer Care and Patient’s Perceptions Before and During COVID-19: Implications for Subsequent SARS-CoV-2 Infection Waves
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Changes in colorectal cancer (CRC) care planning due to the coronavirus disease 2019 (COVID-19) pandemic and associated health-related quality of life (HRQoL) and well-being of patients with CRC are unknown. We report changes in CRC care and patient-reported outcomes (PROs) including HRQoL, distress, and loneliness during the first wave of SARS-CoV-2.In April 2020, 4,984 patients included in the nationwide Prospective Dutch Colorectal Cancer cohort were invited to complete a COVID-19-specific questionnaire, together with the validated EORTC QLQ-C30, De Jong Gierveld, and HADS. Clinical data were obtained from the Netherlands Cancer Registry. Scores were compared with the year prior to COVID-19, and with an age- and sex-matched control population during COVID-19.In total, 3,247 (65.1%) patients responded between April and June 2020. Seventeen percent of patients had cancelled/postponed/changed hospital visits into a telephone- or video consult while 5.3% had adjusted/postponed/cancelled treatment. Compared to controls, patients reported worse HRQoL, but comparable distress and less social loneliness (patients = 21.2%; controls = 32.9%). Compared to pre-COVID-19, clinically meaningful deterioration of HRQoL was more prevalent in patients with changes in cancer care planning than in patients without changes. Prior to undergoing or currently undergoing treatment, and infection worries were associated with lower HRQoL.CRC patients reported equal anxiety and depression, but worse HRQoL than the control population. Changes in care planning were associated with deterioration of HRQoL and increased anxiety. In case of one or more risk factors, healthcare specialists should discuss (mental) health status and possible support during future SARS-CoV-2 infection waves or comparable pandemics.
JNCI Cancer Spectrum , article en libre accès, 2020