Increasing HPV Vaccination among Low-income, Ethnic Minority Adolescents: Effects of a Multicomponent System Intervention through a County Health Department Hotline
Menée entre 2013 et 2016 par enquête auprès de 238 adolescents défavorisés et issus de minorités ethniques (âge : 11-17 ans ; durée de suivi : 9 mois), cette étude analyse l'effet, sur le taux de vaccination contre le papillomavirus humain, d'une intervention téléphonique combinant information pédagogique et orientation vers un vaccin à bas prix ou gratuit
Background: Introduction of the human papillomavirus (HPV) vaccine in 2006 was a game-changing advance in cancer control. Despite the vaccine's potential cancer prevention benefits, uptake remains low. We utilized a randomized design to evaluate a multicomponent intervention to improve HPV vaccine uptake among low-income, ethnic minority adolescents seeking services through a county health department telephone hotline. Methods: Hotline callers who were caregivers of never-vaccinated adolescents (11-17 years) were randomized by call-week to intervention or control conditions. The intervention included brief telephone and print education, delivered in multiple languages, and personalized referral to a low-cost/free vaccine provider. Participants completed baseline (n=238), 3-month (n=215), and 9-month (n=204) telephone follow-up surveys. Results: HPV vaccine initiation rates increased substantially by 9-month follow-up overall, though no differences were observed between intervention and control groups (45% vs. 42%, respectively, p>0.05). We also observed significant improvements in perceived HPV risk, barriers to vaccination, and perceived knowledge in both study conditions (p<0.05). Conclusions: A low-intensity county hotline intervention did not produce a greater increase in HPV vaccination rates than routine practice. However, 44% of unvaccinated adolescents in both conditions received at least one dose of the vaccine, which can be viewed as a successful public health outcome. Future studies should evaluate more intensive interventions that address accessing and utilizing services in complex safety net settings. Impact: Study results suggest the need for investigators to be aware of the potential priming effects of study participation, which may obscure the effect of low-intensity interventions.