Geographic distribution of malignant mesothelioma incidence and survival in Australia
Menée en Australie, cette étude analyse les disparités géographiques dans l'incidence du mésothéliome et dans la survie
Objectives : To understand the geographic distribution of and area-level factors associated with malignant mesothelioma incidence and survival in Australia. Materials and Methods : Generalised linear models and Bayesian spatial models were fitted using populationregistry data. Area-level covariates were socioeconomic quintile, remoteness categoryand state or territory. The maximised excess events test was used to test for spatialheterogeneity. Results : There was strong evidence of spatial differences in standardised incidence rates formalignant mesothelioma but survival was uniformly poor. Incidence rates varied bystate or territory and were lower in remote areas. Patterns in the geographic distributionof modelled incidence counts for malignant mesothelioma differed substantially frompatterns of standardised incidence rates. Conclusions : Geographic variation in the modelled incidence counts of malignant mesothelioma demonstratesvarying demand for diagnostic and management services. The long latency period forthis cancer coupled with migration complicates any associations with patterns of exposure,however some of the geographic distribution of diagnoses can be explained by the locationof historical mines and asbestos-related industries.