Fatty foods and the risk of bladder cancer: a case-control study
Menée en Chine par questionnaire auprès de 292 témoins et 113 patients atteints d'un cancer de la vessie récemment diagnostiqué, cette étude analyse l'association entre le type d'aliments gras consommés et le risque de développer la maladie
Objective : To explore the association between dietary fatty foods and the risk of bladder cancer Methods : Newly diagnosed bladder cancer patients (n = 113) and 292 controls were recruited. Food frequency questionnaire (FFQ) was used to investigate the food intake within one year. Multivariate logistic regression model was used to estimated odds ratio (OR) between different types of fatty food consumption and bladder cancer. Results : The consumptions of soybean oil, the largest proportion of cooking oil, in both groups were extremely higher than the Chinese recommended dietary intake, especially in the case group. Higher intake of red meat was also observed in bladder cancer cases. While lower intakes of marine fish, egg, milk &daily products and nuts were observed in cases. After adjusting for potential confounders, the intakes of marine fish and milk & daily products were negatively correlated with bladder cancer, with the adjusted OR = 0.28 (95% CI 0.15, 0.55) and 0.36(95% CI 0.19, 0.69). Total nuts were related to a 76% reduction in BC risk (OR 0.24; 95% CI 0.12, 0.48). There was clear and positive association between soybean oil and BC risk with OR = 3.47 (95 % CI 1.69, 7.14). In stratified analyses by sex and smoking status, the relationship was similar for most results, with the exception of milk & dairy products. The negative correlation between milk & dairy products and BC risk was only found in male, and milk & dairy products and bladder cancer risk was irrelevant by smoking status. No significant association was found between the intakes of other foods and bladder cancer risk. Conclusions : Intake of nuts and marine fish may be beneficial for the prevention of bladder cancer. The protective effect of milk & dairy products was only found in male patients with BC. While high soybean oil intake was a risk factor for BC.
Nutrition 2022