Advancing Rapid Cycle Research in Cancer Care Delivery: A National Cancer Institute Workshop Report
Cet article présente les conclusions issues d'un séminaire, organisé en février 2022 par le "National Cancer Institute" et rassemblant des experts, des chercheurs, des cliniciens et des patients, dont l'objectif était de déterminer la manière dont les méthodes de recherche interventionnelle à cycle rapide peuvent être utilisées pour générer des résultats utiles à l'amélioration des pratiques cliniques de routine
There is growing recognition to increase the pace and efficiency of generating research findings that can be used to improve delivery of cancer-related care and outcomes. To address this issue, the National Cancer Institute (NCI) convened subject matter experts, researchers, clinicians, and patients for a two-day virtual meeting in February 2022. The purpose of this meeting was to identify how rapid cycle interventional research methods can be used to generate findings useful in improving routine clinical practice. The meeting yielded an initial conceptualization of rapid cycle interventional research as being comprised of six key elements: use of iterative study designs; reliance on proximal primary outcomes; early and continued engagement with community and clinical partners; use of existing data sources to measure primary outcomes; facilitative features of the study setting and context; and consideration of appropriate rigor relative to intended use of findings. The meeting also identified the types of study designs that can be leveraged to conduct rapid cycle interventional research and provided examples of these; considered this approach from the perspective of key partners; described the clinical and data infrastructure, research resources, key collaborations needed to support this work; identified research topics best addressed using this approach; and considered needed methodological advances. NCI is committed to exploring opportunities to encourage further development and application of this research approach as a means for better promoting improvements in the delivery of cancer-related care.
Journal of the National Cancer Institute , article en libre accès, 2022