Incidence of HPV-related cancers among males and females 15-34 years old in the US
Menée à partir de données 2002-2019 de la base "United States Cancer Statistics", cette étude analyse l'effet de la politique de vaccination contre le papillomavirus humain (HPV) sur l'incidence des cancers liés au HPV, par tranche d'âge et en fonction du sexe
Post-market surveillance of the incidence of Human papillomavirus (HPV)-related cancers is essential to monitor the effectiveness of HPV vaccines. We directly compared HPV-related cancer incidences during the pre- and post- vaccine era to assess the effects of HPV vaccination among vaccine-eligible age groups in the US using data from United States Cancer Statistics (USCS) database. The 5–year average annual incidence rates for HPV-related cancers decreased in 2015–2019 compared to 2002–2006 among females 15–24 years old and 25–34 years old. Overall, a decrease in young males was not observed while males 25-34 years old experienced a slight decline in oropharyngeal squamous cell carcinoma between 2005-09 and 2015-19. Incidence rates for HPV-related cancers significantly decreased in the vaccine era compared to the pre-vaccine era among females 15-34 years old, suggesting the potential early effects of the introduction of HPV vaccination in the US.
JNCI Cancer Spectrum 2023