Cumulative incidence of anal cancer since HIV or AIDS diagnosis in the United States
Menée aux Etats-Unis, cette étude analyse l'incidence cumulée du cancer de l'anus chez les patients infectés par le VIH ou diagnostiqués avec le SIDA
Treatment of screen-detected anal high-grade squamous intraepithelial lesions has been shown to effectively reduce the incidence of invasive anal cancer in people with HIV (PWH). We provide population-based estimates of cumulative incidence of anal cancer by risk group and age at HIV and/or AIDS diagnosis. The 0–10-year cumulative incidence of anal cancer for men who have sex with men (MSM) aged <30 years at HIV diagnosis was 0.17% (95% CI = 0.13–0.20%) compared to 0.04% (0.02–0.06%) in other males and 0.03% (0.01–0.04%) in females. For MSM with a diagnosis of AIDS aged <30, the 0–10-year cumulative incidence was 0.42% (0.35–0.48%). Among PWH, MSM are at the greatest risk of anal cancer and those with a diagnosis of AIDS had higher risk than those without AIDS. These estimates may inform recommendations for priority populations who could benefit most from anal cancer screening and treatment.