Patterns of recurrence in FIGO 2018 stage IB1-IB2 cervical cancer: Comparison between minimally invasive and abdominal radical hysterectomy
Menée auprès de 360 patientes atteintes d'un cancer du col de l'utérus de stade IB1-IB2 et ayant subi une hystérectomie radicale, cette étude analyse les schémas de récivide de la maladie en fonction de la technique chirurgicale utilisée (laparotomique ou mini-invasive)
Introduction: Aim of our study was to evaluate whether the different laparotomic (ARH) or minimally invasive (laparoscopic and robotic) approaches (MIS) in FIGO stage IB1-IB2 cervical cancer, present different patterns of recurrence of the disease. The secondary endpoint of the study was the evaluation of the variables most involved with the risk of relapse and therefore lower DFS and OS. Materials and methods: The study included patients with definitive histological diagnosis of squamous or adenocarcinoma FIGO 2018 stage IB1-IB2 cervical cancer who underwent minimally invasive or abdominal radical hysterectomy from 2001 to 2018. Results: The study included 360 patients, and 59 patients (16.4%) reported disease relapses. ARH group was not associated with different pattern of recurrence than MIS group (p = 0.14) and majority of recurrences were reported on the vaginal vault in both groups. Moreover, there was no statistically significant difference regarding DFS (p = 0.52), and OS (p = 0.29) between the ARH group and the MIS group. Conclusion: MIS, in FIGO stage IB1-IB2 cervical cancer, is not associated with different relapse patterns compared to ARH, nor with a higher risk of distance metastasis and finally, without significant difference in terms of DFS and OS. More studies are needed to determine the factors that modify the site of relapse.