Can Preoperative Radiological Identification of Lung Tumor Invasiveness Be Improved?
Menée sur 620 patients atteints d'un adénocarcinome du poumon (âge moyen : 53,5 ans ; 71 % de femmes), cette étude évalue la performance d'une tomographie numérique à haute résolution pour diagnostiquer un envahissement tumoral pathologique
In this issue of the JAMA Network Open, Ye and colleagues reported a prospective multicenter diagnostic study from China. They recruited patients who underwent lung resection for ground-glass opacity (GGO)–featured lung tumors and analyzed preoperative high-resolution computed tomography (HRCT) images using a set of radiologic criteria to identify pathological tumor invasion. The overall diagnostic accuracy was 83.0% (95% CI, 79.8%-85.8%), sensitivity was 82.4% (95% CI, 76.9%-87.1%), and specificity was 83.3% (95% CI, 79.2%-86.9%). Tumor size and solid component size were the 2 independent factors during multivariable analysis, with a cutoff for the solid component size at 6 mm.
JAMA Network Open , éditorial en libre accès, 2022